Major quantitative trait loci influencing milk production and conformation traits in Guernsey dairy cattle detected on Bos taurus autosome 19

The goal of this study was to identify potential quantitative trait loci (QTL) for 27 production, fitness, and conformation traits Guernsey cattle through genome-wide association (GWA) analyses, with extra emphasis on BTA19, where major QTL were observed several traits. Animals' de-regressed predicted transmitting abilities (PTA) from the December 2018 traditional US evaluation used as phenotypes. All included in analyses predictor animals reference population, ranging 1,077 1,685 different Single-trait GWA carried out by a mixed-model approach all using imputed high-density genotypes. A detected influencing milk production traits, livability cattle, most significant SNP lie region 26.2 28.3 Mb. myosin heavy chain 10 (MYH10) gene residing within found be highly associated body dairy cattle. After initial which suggested that many are linkage one another, conditional fine mapping. top BTA19 fixed covariables model, at time, until no more BTA19. fine-mapping applied, only 1 but multiple, independent protein yield, form, stature. In addition, haplotype hosts traced born 1954. is common breed, indicating long-term influence population.